Int Adv Otol. 2012;8(2):154-157.
When running an allograft tympano-ossicular systems tissue bank, compliance with national and European Union regulations on traceability, quality assurance and safety procedures to reduce the risk of transmitting disease is critical. The intracranial bone plug technique described by Schuknecht is an established approach to procure allograft tympano-ossicular systems. However, this technique entails separate removal of the allograft tympano-ossicular systems from the bone plug, the dura mater is encountered and it is esthetically invasive to the donor. The transmeatal technique is a feasible alternative, which is less time-consuming, avoids contact with the dura mater and is esthetically less invasive to the donor. The regulatory guidelines for graft procurement related to variant Creutzfeldt-Jakob's disease could be reconsidered when the transmeatal technique is used.